meridia weight loss
meridia weight loss
Buy meridia weight loss online A new study from Mexico shows that Meridia is effective, with participants who took the drugs meeting their goal of a 5% loss of total body weight over six months. But a significant number of study participants who took a placebo, or sugar pill, met that goal as well.
The Mexican study, which involved 109 obese patients, is reported in the February issue of the International Journal of Obesity. All the patients were advised to eat a low-calorie, high-carbohydrate, and low-fat diet; half took Meridia and half took the placebo. Researchers looked at the participants' body mass indexes (BMI) and hip-to-waist ratios as well as their weight.
Meridia is an appetite suppressant that helps to curb food cravings. It works through the serotonin system, much as antidepressants do. The study's authors note that the main side effect of Meridia is a dry mouth, although some patients experienced constipation, elevated blood pressure, and a rapid pulse.
"Sibutramine induces significant loss of body weight, BMI and waist [circumference], but does not significantly affect cardiovascular function," the authors write.
This statement concerns Richard Dickey, MD, president of the American Academy of Clinical Endocrinologists. "There have been patients who have had clinically significant rises in blood pressure and pulse with sibutramine," says Dickey, who reviewed the study for WebMD. "Just because these people did a study with 109 patients doesn't mean it doesn't do that."
Mike Myers, MD, who also reviewed the study for WebMD, agrees with Dickey's take on the study. "Sibutramine is not a wonder drug, [but] it does have its place and it can assist with weight loss," he says. "Assist" is the operative word, as diet and exercise are still very important to any weight loss program, both physicians say. Myers is a primary practice physician in Los Alamitos, Calif. A member of the North American Association for the Study of Obesity, he specializes in weight management and eating disorders.
One of the reasons it's so difficult to lose excess weight through diet alone is our makeup, Myers says. "Fortunately, or unfortunately, depending on how you look at things, we have been created to be extremely efficient organisms to survive famine," he explains. When calories are restricted, the body lowers metabolism to stave off starvation, whether a person is obese or not. The only way to jump-start the metabolism (the body's ability to convert food into energy) is through exercise.
One caution for both physicians and patients, Dickey says, is that a patient should lose at least four pounds in the first month of taking the drug. If this doesn't happen, there is something wrong with the program or with the drug. "It's usually with the program," he says. "In other words, their adherence to the caloric restriction, activity, and other behavior and lifestyle changes is undermining any benefit of the drug."
The authors of the study note that after the drug was stopped, the patients regained nearly 25% of the weight they'd lost, again emphasizing the need for diet, activity, and lifestyle changes.
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